The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction

He Ya Ping; Hou Ming Yan; Wu Yv; Peng Hai Yan

doi:doi:10.11648/j.ijcm.20220601.13

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The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction

He Ya Ping, Hou Ming Yan, Wu Yv, Peng Hai Yan

Published in International Journal of Chinese Medicine (Volume 6, Issue 1)

Received: 16 January 2022 Accepted: 27 January 2022 Published: 9 February 2022

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Abstract

Background: Si-Miao Yong-An Decoction is composed of four herbs: honeysuckle, Radix Sophora, Angelica and Licorice. It has the functions of clearing away heat and detoxification, promoting blood circulation and clearing collaterals. It is a famous ancient formula for the treatment of gangrene, and is now widely used in the treatment of multiple diseases in various systems. Objective: To explore the anticancer action of Si-Miao Yong-An decoction in the clinical application of the treatment of some kinds of malignant tumors. Methods: This paper reviews the sections in classical TCM books and recent report of clinical study of Si-Miao Yong-An Decoction in the treatment of cervical cancer, breast cancer, nasopharyngeal cancer, oral cancer, gastric cancer and etc. Results: The composition of the prescription was first recorded in Shen Yi Mi Zhuan in Han dynasty, and also recorded in the book of Shi Shi Mi Lv and Yan Fang Xin Bian, and it was formally named in Journal of TCM in the year of 1958. It was useful in relieving the clinical symptoms and elevating the life quality besides preventing the recurrence and metastasis of cancer. Conclusion: Si-Miao Yong-An Decoction is effective in treating various malignant tumors and the related complications of the syndrome of blood stasis and heat-toxin. It is promising to provide a new direction for better exploration of traditional Chinese medicine and its application in the treatment of malignant tumors in the future.

Published in	International Journal of Chinese Medicine (Volume 6, Issue 1)
DOI	10.11648/j.ijcm.20220601.13
Page(s)	15-19
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Si-Miao Yong-An Decoction, Anticancer, Traditional Chinese Medicine (TCM), Clinical Study

References

[1]	Li Ji, Lian Jian-Wei. Formulaology. [M]. Peking: China Press of Traditional Chinese Medicine, 2016: 297-8.
[2]	Peng Jing-Shan. Hua Tuo Shen Yi Mi Zhuan. [M]. Da Lian: Liao Ning Science and Technology Press, 1982: 140.
[3]	Chen Shi-Duo. Shi Shi Mi Lv. [M]. Peking: China Press of Traditional Chinese Medicine, 1991: 2, 220.
[4]	Bao Xiang-Ao. Yan Fang Xin Bian [M]. Shanghai: Second Military Medical University Press, 2007: 72.
[5]	TCM department of NO. 1 hospital of He-Bei province Tian-Jin administrative region. Report of the treatment of thromboangiitis obliterans [J]. Journal of Traditional Chinese Medicine, 1958 (11): 752-3.
[6]	Buskwofie A, David-West G, Clare CA. A Review of Cervical Cancer: Incidence and Disparities [J]. J Natl Med Assoc. 2020; 112 (2): 229-232.
[7]	Sharma S, Deep A, Sharma AK. Current Treatment for Cervical Cancer: An Update [J]. Anticancer Agents Med Chem. 2020; 20 (15): 1768-1779.
[8]	Kaneyasu, Yuko et al. “A multi-institutional survey of the quality of life after treatment for uterine cervical cancer: a comparison between radical radiotherapy and surgery in Japan.” Journal of radiation research [J]. 2021; 62 (2): 269-284.
[9]	Dong Jvan-Jvan, Qi Rong, Zhang Xiao-Hua, et al. Professor Wu Qvan-Sheng’s experience of treating lower extremity lymphedema after radical operation of gynecological malignant tumor from syndrome differentiation of Qi and blood [J]. Guangming Journal of Chinese Medicine. 2016, 31 (20): 2941-2943.
[10]	Huang Li, Xiang Ming-Hong, Li Qing-Song, et al. The clinical experience of treating lower extremity edema after cervical cancer surgery with Si-Miao Yong-An decoction. Chinese Medicine Modern Distance Education of China [J]. 2018, 16 (01): 84-86.
[11]	Fahad Ullah M. Breast Cancer: Current Perspectives on the Disease Status [J]. Adv Exp Med Biol. 2019; 1152: 51-64.
[12]	Montagnese C, Porciello G, Vitale S, et al. Quality of Life in Women Diagnosed with Breast Cancer after a 12-Month Treatment of Lifestyle Modifications [J]. Nutrients. 2020; 13 (1): 136.
[13]	Kaufman CS. Increasing Role of Oncoplastic Surgery for Breast Cancer [J]. Curr Oncol Rep. 2019; 21 (12): 111.
[14]	Al-Hilli Z, Wilkerson A. Breast Surgery: Management of Postoperative Complications Following Operations for Breast Cancer [J]. Surg Clin North Am. 2021; 101 (5): 845-863.
[15]	Schmidt ME, Scherer S, Wiskemann J, Steindorf K. Return to work after breast cancer: The role of treatment-related side effects and potential impact on quality of life [J]. Eur J Cancer Care (Engl). 2019; 28 (4): e13051.
[16]	Gong Wei. The effective examples of edema in the upper arm after surgery of breast cancer patients treated by Modified Si-Miao Yong-An decoction [J]. Journal of Nanjing University of Traditional Chinese Medicine. 2006 (04): 257-258.
[17]	Huang Xiao-Na, Wu Zheng-Long. 30 cases of edema in the upper arm after surgery of breast cancer patients treated by Modified Si-Miao Yong-An decoction [J]. Henan Traditional Chinese Medicine. 2014, 34 (12): 2398-2399.
[18]	Lee HM, Okuda KS, González FE, Patel V. Current Perspectives on Nasopharyngeal Carcinoma [J]. Adv Exp Med Biol. 2019; 1164: 11-34.
[19]	Lang J, Hu C, Lu T, Pan J, Lin T. Chinese expert consensus on diagnosis and treatment of nasopharyngeal carcinoma: evidence from current practice and future perspectives [J]. Cancer Manag Res. 2019; 11: 6365-6376.
[20]	WEI Xue-Yan, LI Ying, HU Desheng. Nutritional Status and Its Influencing Factors of Nasopharyngeal Carcinoma Patients During Chemoradiotherapy [J]. Cancer Research on Prevention and Treatment. 2020; 47 (7): 524-530.
[21]	Lu Wei, Shen Zheng-Jie, Cheng Hai-Bo. The clinical application of Modified Si-Miao Yong-An decoction in treating malignant tumors [J]. China Journal of Traditional Chinese Medicine and Pharmacy. 2017, 32 (04): 1601-1603.
[22]	Wong T, Wiesenfeld D. Oral Cancer [J]. Aust Dent J. 2018; 63 Suppl 1: S91-S99.
[23]	Valdez JA, Brennan MT. Impact of Oral Cancer on Quality of Life [J]. Dent Clin North Am. 2018; 62 (1): 143-154.
[24]	Chen YY, Wang CC, Wu WT, et al. Trajectories of returning to work and its impact on survival in survivors with oral cancer: A 5-year follow-up study [J]. Cancer. 2020; 126 (6): 1225-1234.
[25]	Xiao Yan-Bo, Zhang Li, Li Qun, et al. Intervention effect of Simiao Yong-An Decoction on OSF carcinogenesis and expression of Wnt pathway-related protein [J]. J Clin Stomatol, 2019, 35 (10): 590-594.
[26]	Arnold M, Ferlay J, van Berge Henegouwen MI, Soerjomataram I. Global burden of oesophageal and gastric cancer by histology and subsite in 2018 [J]. Gut. 2020; 69 (9): 1564-1571.
[27]	Venerito M, Ford AC, Rokkas T, Malfertheiner P. Review: Prevention and management of gastric cancer. Helicobacter [J]. 2020; 25 Suppl 1: e12740.
[28]	Johnston FM, Beckman M. Updates on Management of Gastric Cancer [J]. Curr Oncol Rep. 2019; 21 (8): 67.
[29]	Jiang Ling. Effect of Simiao Yongan Tang Combined with Xihuang Wan for Ulcerative Type Gastric Cancer and Its Metadherin Protein [J]. JOURNAL OF NEW CHINESE MEDICINE. 2016, 48 (08): 215-217.
[30]	Dai Yvn. TCM botanic physician Zhang Pei-Yv’s experience in treating thyroid cancer [D]. Beijing University of traditional Chinese Medicine. 2014.
[31]	Zhao Yv-Rong, Shu Qi-Jin. Professor Shu Qijin' s Experiences in Treating Cancer-Related Aphtha Based on Triple Energizer Syndrome Differentiation [J]. Journal of Chengdu university of TCM. 2020, 43 (04): 51-3.

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APA Style

He Ya Ping, Hou Ming Yan, Wu Yv, Peng Hai Yan. (2022). The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction. International Journal of Chinese Medicine, 6(1), 15-19. https://doi.org/10.11648/j.ijcm.20220601.13

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ACS Style

He Ya Ping; Hou Ming Yan; Wu Yv; Peng Hai Yan. The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction. Int. J. Chin. Med. 2022, 6(1), 15-19. doi: 10.11648/j.ijcm.20220601.13

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AMA Style

He Ya Ping, Hou Ming Yan, Wu Yv, Peng Hai Yan. The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction. Int J Chin Med. 2022;6(1):15-19. doi: 10.11648/j.ijcm.20220601.13

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@article{10.11648/j.ijcm.20220601.13,
  author = {He Ya Ping and Hou Ming Yan and Wu Yv and Peng Hai Yan},
  title = {The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction},
  journal = {International Journal of Chinese Medicine},
  volume = {6},
  number = {1},
  pages = {15-19},
  doi = {10.11648/j.ijcm.20220601.13},
  url = {https://doi.org/10.11648/j.ijcm.20220601.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20220601.13},
  abstract = {Background: Si-Miao Yong-An Decoction is composed of four herbs: honeysuckle, Radix Sophora, Angelica and Licorice. It has the functions of clearing away heat and detoxification, promoting blood circulation and clearing collaterals. It is a famous ancient formula for the treatment of gangrene, and is now widely used in the treatment of multiple diseases in various systems. Objective: To explore the anticancer action of Si-Miao Yong-An decoction in the clinical application of the treatment of some kinds of malignant tumors. Methods: This paper reviews the sections in classical TCM books and recent report of clinical study of Si-Miao Yong-An Decoction in the treatment of cervical cancer, breast cancer, nasopharyngeal cancer, oral cancer, gastric cancer and etc. Results: The composition of the prescription was first recorded in Shen Yi Mi Zhuan in Han dynasty, and also recorded in the book of Shi Shi Mi Lv and Yan Fang Xin Bian, and it was formally named in Journal of TCM in the year of 1958. It was useful in relieving the clinical symptoms and elevating the life quality besides preventing the recurrence and metastasis of cancer. Conclusion: Si-Miao Yong-An Decoction is effective in treating various malignant tumors and the related complications of the syndrome of blood stasis and heat-toxin. It is promising to provide a new direction for better exploration of traditional Chinese medicine and its application in the treatment of malignant tumors in the future.},
 year = {2022}
}

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TY  - JOUR
T1  - The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction
AU  - He Ya Ping
AU  - Hou Ming Yan
AU  - Wu Yv
AU  - Peng Hai Yan
Y1  - 2022/02/09
PY  - 2022
N1  - https://doi.org/10.11648/j.ijcm.20220601.13
DO  - 10.11648/j.ijcm.20220601.13
T2  - International Journal of Chinese Medicine
JF  - International Journal of Chinese Medicine
JO  - International Journal of Chinese Medicine
SP  - 15
EP  - 19
PB  - Science Publishing Group
SN  - 2578-9473
UR  - https://doi.org/10.11648/j.ijcm.20220601.13
AB  - Background: Si-Miao Yong-An Decoction is composed of four herbs: honeysuckle, Radix Sophora, Angelica and Licorice. It has the functions of clearing away heat and detoxification, promoting blood circulation and clearing collaterals. It is a famous ancient formula for the treatment of gangrene, and is now widely used in the treatment of multiple diseases in various systems. Objective: To explore the anticancer action of Si-Miao Yong-An decoction in the clinical application of the treatment of some kinds of malignant tumors. Methods: This paper reviews the sections in classical TCM books and recent report of clinical study of Si-Miao Yong-An Decoction in the treatment of cervical cancer, breast cancer, nasopharyngeal cancer, oral cancer, gastric cancer and etc. Results: The composition of the prescription was first recorded in Shen Yi Mi Zhuan in Han dynasty, and also recorded in the book of Shi Shi Mi Lv and Yan Fang Xin Bian, and it was formally named in Journal of TCM in the year of 1958. It was useful in relieving the clinical symptoms and elevating the life quality besides preventing the recurrence and metastasis of cancer. Conclusion: Si-Miao Yong-An Decoction is effective in treating various malignant tumors and the related complications of the syndrome of blood stasis and heat-toxin. It is promising to provide a new direction for better exploration of traditional Chinese medicine and its application in the treatment of malignant tumors in the future.
VL  - 6
IS  - 1
ER  -

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Author Information

He Ya Ping

The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China
Hou Ming Yan

The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China
Wu Yv

The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China
Peng Hai Yan

The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China

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APA Style

He Ya Ping, Hou Ming Yan, Wu Yv, Peng Hai Yan. (2022). The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction. International Journal of Chinese Medicine, 6(1), 15-19. https://doi.org/10.11648/j.ijcm.20220601.13

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ACS Style

He Ya Ping; Hou Ming Yan; Wu Yv; Peng Hai Yan. The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction. Int. J. Chin. Med. 2022, 6(1), 15-19. doi: 10.11648/j.ijcm.20220601.13

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AMA Style

He Ya Ping, Hou Ming Yan, Wu Yv, Peng Hai Yan. The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction. Int J Chin Med. 2022;6(1):15-19. doi: 10.11648/j.ijcm.20220601.13

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@article{10.11648/j.ijcm.20220601.13,
  author = {He Ya Ping and Hou Ming Yan and Wu Yv and Peng Hai Yan},
  title = {The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction},
  journal = {International Journal of Chinese Medicine},
  volume = {6},
  number = {1},
  pages = {15-19},
  doi = {10.11648/j.ijcm.20220601.13},
  url = {https://doi.org/10.11648/j.ijcm.20220601.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20220601.13},
  abstract = {Background: Si-Miao Yong-An Decoction is composed of four herbs: honeysuckle, Radix Sophora, Angelica and Licorice. It has the functions of clearing away heat and detoxification, promoting blood circulation and clearing collaterals. It is a famous ancient formula for the treatment of gangrene, and is now widely used in the treatment of multiple diseases in various systems. Objective: To explore the anticancer action of Si-Miao Yong-An decoction in the clinical application of the treatment of some kinds of malignant tumors. Methods: This paper reviews the sections in classical TCM books and recent report of clinical study of Si-Miao Yong-An Decoction in the treatment of cervical cancer, breast cancer, nasopharyngeal cancer, oral cancer, gastric cancer and etc. Results: The composition of the prescription was first recorded in Shen Yi Mi Zhuan in Han dynasty, and also recorded in the book of Shi Shi Mi Lv and Yan Fang Xin Bian, and it was formally named in Journal of TCM in the year of 1958. It was useful in relieving the clinical symptoms and elevating the life quality besides preventing the recurrence and metastasis of cancer. Conclusion: Si-Miao Yong-An Decoction is effective in treating various malignant tumors and the related complications of the syndrome of blood stasis and heat-toxin. It is promising to provide a new direction for better exploration of traditional Chinese medicine and its application in the treatment of malignant tumors in the future.},
 year = {2022}
}

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TY  - JOUR
T1  - The Clinical Research on the Anticancer Action of Si-Miao Yong-An Decoction
AU  - He Ya Ping
AU  - Hou Ming Yan
AU  - Wu Yv
AU  - Peng Hai Yan
Y1  - 2022/02/09
PY  - 2022
N1  - https://doi.org/10.11648/j.ijcm.20220601.13
DO  - 10.11648/j.ijcm.20220601.13
T2  - International Journal of Chinese Medicine
JF  - International Journal of Chinese Medicine
JO  - International Journal of Chinese Medicine
SP  - 15
EP  - 19
PB  - Science Publishing Group
SN  - 2578-9473
UR  - https://doi.org/10.11648/j.ijcm.20220601.13
AB  - Background: Si-Miao Yong-An Decoction is composed of four herbs: honeysuckle, Radix Sophora, Angelica and Licorice. It has the functions of clearing away heat and detoxification, promoting blood circulation and clearing collaterals. It is a famous ancient formula for the treatment of gangrene, and is now widely used in the treatment of multiple diseases in various systems. Objective: To explore the anticancer action of Si-Miao Yong-An decoction in the clinical application of the treatment of some kinds of malignant tumors. Methods: This paper reviews the sections in classical TCM books and recent report of clinical study of Si-Miao Yong-An Decoction in the treatment of cervical cancer, breast cancer, nasopharyngeal cancer, oral cancer, gastric cancer and etc. Results: The composition of the prescription was first recorded in Shen Yi Mi Zhuan in Han dynasty, and also recorded in the book of Shi Shi Mi Lv and Yan Fang Xin Bian, and it was formally named in Journal of TCM in the year of 1958. It was useful in relieving the clinical symptoms and elevating the life quality besides preventing the recurrence and metastasis of cancer. Conclusion: Si-Miao Yong-An Decoction is effective in treating various malignant tumors and the related complications of the syndrome of blood stasis and heat-toxin. It is promising to provide a new direction for better exploration of traditional Chinese medicine and its application in the treatment of malignant tumors in the future.
VL  - 6
IS  - 1
ER  -

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